You have 9 free searches left this month | for more free features.
Clincosm LogoSign in Get a demo

RAS or RAF oncogenes, Inhibition of MEK pathway, inhibition cancer cell proliferation promising anti-cancer therapeutic strategy.

Showing 1 - 25 of >10,000
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED

Resistance-associated Mutations in Metastatic Lung Cancer

Recruiting
  • Lung Cancer
  • Liquid biopsy
  • Monza, MB, Italy
    Fondazione IRCCS San Gerardo dei Tintori
Oct 10, 2023

Klotho _ LRP-6 _ Gastric Adenocarcinoma

Not yet recruiting
  • Gastric Adenocarcinoma
  • +2 more
  • Prognostic study
  • (no location specified)
Jan 29, 2023

Advanced or Metastatic Solid Tumors Trial (Naporafinib, Trametinib)

Not yet recruiting
  • Advanced or Metastatic Solid Tumors
  • (no location specified)
Jun 21, 2023

Pancreatic Ductal Adenocarcinoma Trial in Miami (Trametinib, Ruxolitinib, Retifanlimab)

Not yet recruiting
  • Pancreatic Ductal Adenocarcinoma
  • Miami, Florida
    University of Miami
Jun 27, 2022

NSCLC Trial in Charleston (Sotorasib and Tarloxotinib)

Recruiting
  • Non-Small Cell Lung Cancer
  • Sotorasib and Tarloxotinib
  • Charleston, South Carolina
    Hollings Cancer Center at Medical University of South Carolina
Mar 28, 2022

Melanoma, Solid Tumor Trial in Korea, Republic of, Spain, United States (DAY101, Pimasertib Hydrochloride)

Recruiting
  • Melanoma
  • Solid Tumor
  • Los Angeles, California
  • +13 more
Jul 27, 2022

Solid Tumor, ARID1A Gene Mutation Trial in Greenville (Tazemetostat)

Suspended
  • Solid Tumor
  • ARID1A Gene Mutation
  • Greenville, South Carolina
    Prisma Health Cancer Institute
Jan 10, 2023

NSCLC Trial in Goyang-si (BIBW 2992, simvastatin)

Completed
  • Non-small Cell Lung Cancer
  • Goyang-si, Gyeonggi-do, Korea, Republic of
    National Cancer Center
Apr 4, 2022

Metastatic Melanoma Trial in Netherlands (drug, device, procedure)

Terminated
  • Metastatic Melanoma
  • Vemurafenib plus cobimetinib
  • +3 more
  • Amsterdam, Netherlands
  • +9 more
Nov 24, 2022

Aspirin in Combination With Trametinib and Dabrafenib

Not yet recruiting
  • NSCLC
  • +4 more
  • Combind asprin with Trametinib and Dabrafenib
  • (no location specified)
Aug 4, 2023

BRAF V600-mutated Lung Carcinoma Treated With Combination of

Completed
  • Non Small Cell Lung Cancer
  • BRAF V600 Mutation
    • Créteil, France
    • +1 more
    Jun 29, 2022

    Metastatic Colorectal Cancer Trial in France (Folfirinox + regorrafenib)

    Active, not recruiting
    • Metastatic Colorectal Cancer
    • Folfirinox + regorrafenib
    • Nice, Alpes-Maritimes, France
    • +3 more
    Jan 16, 2023

    NSCLC Trial in Amsterdam (Ipilimumab, Cemiplimab, SBRT)

    Recruiting
    • Carcinoma, Non-Small-Cell Lung
    • Amsterdam, Noord-Holland, Netherlands
      Antoni van Leeuwenhoek - Netherlands Cancer Institute
    Jan 10, 2023

    Breast Cancer Trial in Marseille (M1774, Fulvestrant injection)

    Not yet recruiting
    • Breast Cancer
    • Marseille, France
      Institut Paoli Calmettes
    Aug 9, 2023

    Small Cell Lung Cancer Trial in Nice (acetazolamide in combination with platinum and etoposide-based radiochemo)

    Recruiting
    • Small Cell Lung Cancer
    • acetazolamide in combination with platinum and etoposide-based radiochemotherapy
    • Nice, France
      Centre Antoine Lacassagne
    Jan 19, 2023

    Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Trial in Shanghai (Dalpiciclib+cetuximab)

    Recruiting
    • Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
    • Shanghai, Shanghai, China
      the Ninth People's Hospital Affiliated to Shanghai Jiao Tong Uni
    Feb 9, 2023

    Gallbladder Cancer Trial in Varanasi (Everolimus 10 mg, Standard of care)

    Recruiting
    • Gallbladder Cancer
    • Everolimus 10 mg
    • Standard of care
    • Varanasi, UP, India
      Banaras Hindu University
    Apr 18, 2023

    Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Cancer, Circulating Tumor Cell Trial in Montpellier (Detection of

    Recruiting
    • Pancreatic Ductal Adenocarcinoma
    • +2 more
    • Detection of circulating tumor cells expressing Axl: CTC-AXL(+)
    • Montpellier, France
      CHU Montpellier
    Jul 1, 2022

    Anaplastic Thyroid Cancer Trial in Leiden (dabrafenib/trametinib)

    Recruiting
    • Anaplastic Thyroid Cancer
    • Leiden, Zuid-Holland, Netherlands
      Ellen Kapiteijn
    Oct 5, 2023

    Colon Cancer Stage III Trial in Sadat City (ChlorproMAZINE 50 MG, Control)

    Not yet recruiting
    • Colon Cancer Stage III
    • Sadat City, Menoufia, Egypt
      Faculty of Pharmacy, University of Sadat city
    Jun 22, 2022

    Leptomeningeal Metastasis, NSCLC Stage IV, Melanoma Stage IV Trial in Geneva, St Gallen, Zurich (intrathecal nivolumab and

    Recruiting
    • Leptomeningeal Metastasis
    • +2 more
    • intrathecal nivolumab and intrathecal ipilimumab
    • Geneva, Switzerland
    • +2 more
    Dec 18, 2022

    NSCLC Stage IV, Melanoma Stage IV, Unresectable Melanoma Trial in Montréal (Camu Camu Capsules (Camu Camu powder encapsulated

    Recruiting
    • NSCLC Stage IV
    • +3 more
    • Camu Camu Capsules (Camu Camu powder encapsulated (500mg each) + ICI
    • Montréal, Quebec, Canada
      Centre hospitalier de l'Université de Montréal (CHUM)
    Jul 18, 2022

    Advanced Solid Tumor, RAS Mutation, RAF Mutation Trial in Houston, Irving (ABM-168)

    Recruiting
    • Advanced Solid Tumor
    • +3 more
    • Houston, Texas
    • +1 more
    Apr 14, 2023

    Non Small Cell Lung Cancer Trial in Seoul (sotorasib)

    Not yet recruiting
    • Non Small Cell Lung Cancer
    • Seoul, Korea, Republic of
      Yonsei University Health System, Severance Hospital
    Jul 5, 2022

    Tumors Trial in Seoul (abemaciclib+paclitaxel)

    Active, not recruiting
    • Tumors
    • Seoul, Korea, Republic of
      Severance Hospital
    May 30, 2022